Deep Sleep

Melatonin is a key component of deep sleep and a natural hormone that regulates the sleep-wake cycle. It plays a key role in reducing the time it takes to fall asleep and ensures restful sleep. Melatonin also helps to alleviate the subjective sensations of jet lag by adjusting the body to the new daily rhythm.

Scientific Background

Melatonin plays a central role in the regulation of the circadian rhythm and synchronizes the sleep-wake cycle with the external light conditions. This makes it easier to fall asleep and stabilizes the sleep-wake rhythm.

studies

• Zisapel, N. (2018): "New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation." Br J Pharmacol. 175(16):3190-3199. doi: 10.1111/bph.14116.


• Poza, J.J., et al. (2022): "Melatonin in sleep disorders." Neurologia (Engl Ed). 37(7):575-585. doi: 10.1016/j.nrleng.2018.08.004.
  

Ashwagandha, also known as "sleep berry," is an adaptogenic herb that has calming and sleep-inducing properties. It helps you both fall asleep and stay asleep by strengthening the parasympathetic nervous system, the part of the nervous system responsible for rest.

Scientific Background

Studies show that Ashwagandha lowers cortisol levels, which helps reduce stress and improves sleep quality.

studies

• Cheah KL, Norhayati MN, Yaacob LH et al. (2021): Effect of ashwagandha (withania somnifera) extract on sleep: a systematic review and meta-analysis. PLoS One. 16(9):e0257843. doi: 10.1371/journal.pone.0257843.
  


• Langade D, Thackeray V, Kanchi S, et al. (2021): Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: a double-blind, randomized, parallel-group, placebo-controlled study. J Ethnopharmacol. 10:264:113276. doi: 10.1016/j.jep.2020.113276.
  

Lavender has been known since ancient times for its calming and relaxing properties. This natural ingredient relieves stress and anxiety and helps treat sleep disorders.

Scientific Background

Lavender has a calming effect on the central nervous system, which promotes sleep and supports general relaxation.

studies

• Lillehei AS, Halcón LL, Savik K, et al. (2015): Effect of inhaled lavender and sleep hygiene on self-reported sleep issues: a randomized controlled trial. J Altern Complement Med 21(7):430-8. doi: 10.1089/acm.2014.0327.
  
• Karadag E, Samancioglu S, Ozden D, et al. (2017): Effects of aromatherapy on sleep quality and anxiety of patients. Nurs Crit Care. 22(2):105-112. doi: 10.1111/nicc.12198.

Lemon balm, another ingredient in Deep Sleep, is known for its calming effect. It can relieve nervousness and make it easier to fall asleep. Studies have shown that lemon balm extract can reduce the symptoms of anxiety and sleep disorders.

Scientific Background

Lemon balm has a relaxing effect on the gastrointestinal tract and has antispasmodic properties. This calming effect helps prepare the body for restful sleep and improves sleep quality.

studies

• Cases J, Ibarra A, Feuillère N, Roller M, Sukkar SG. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances. Med J Nutrition Metab. 2011 Dec;4(3):211-218. doi: 10.1007/s12349-010-0045-4. Epub 2010 Dec 17. PMID: 22207903; PMCID: PMC3230760.


• Zam W, Quispe C, Sharifi-Rad J, López MD, Schoebitz M, Martorell M, Sharopov F, Fokou PVT, Mishra AP, Chandran D, Kumar M, Chen JT, Pezzani R. An Updated Review on The Properties of Melissa officinalis L.: Not Exclusively Anti-anxiety. Front Biosci (Schol Ed). 2022 Jun 7;14(2):16. doi: 10.31083/j.fbs1402016. PMID: 35730441.