Evidencia científica
Nuestra bibliografía te ofrece referencias para profundizar en el estudio de las bacterias, la salud humana y la ciencia detrás de nuestros productos. En una bibliografía científica, las fuentes se enumeran con todos los detalles necesarios. Esto te brinda una visión precisa de las investigaciones en las que nos basamos.
El microbioma
General
1. Sender, R., et al. (2016). Revised estimates for the number of human and bacterial cells in the body. PLoS biology, 14(8)
2. Eckburg, P.B., et al. (2005). Diversity of the human intestinal microbial flora. science, 308(5728), 1635-1638.
3. Sommer, F., & Bäckhed, F. (2013). The gut microbiota—masters of host development and physiology. Nature Reviews Microbiology, 11(4), 227.
... y sus funciones
digestion
1. Aziz, Q., et al. (2013). Gut microbiota and gastrointestinal health: current concepts and future directions. Neurogastroenterology & Motility, 25(1), 4-15.
2. Rowland, I., et al. (2018). Gut microbiota functions: metabolism of nutrients and other food components. European journal of nutrition, 57(1), 1-24.
Función barrera de la mucosa intestinal
1. Suzuki, T. (2013). Regulation of intestinal epithelial permeability by tight junctions. Cellular and molecular life sciences, 70(4), 631-659.
2. Hu, M.D., et al. (2018). Policing the intestinal epithelial barrier: innate immune functions of intraepithelial lymphocytes. Current pathobiology reports, 6(1), 35-46.
Sistema inmune
1. Webb, C.R., et al. (2016). Protective and pro-inflammatory roles of intestinal bacteria. Pathophysiology, 23(2), 67-80.
2. Tlaskalová-Hogenová, H., et al. (2004). Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseases. Immunology letters, 93(2-3), 97-108.
3. Allaire, J.M., (2018). The intestinal epithelium: central coordinator of mucosal immunity. Trends in immunology, 39(9), 677-696.
4. Thaiss, C.A., (2016). The microbiome and innate immunity. Nature, 535(7610), 65.
Metabolismo
1. Kasińska, M. A., & Drzewoski, J. (2015). Effectiveness of probiotics in type 2 diabetes: a meta-analysis. Pol Arch Med Wewn, 125(11), 803-813.
2. Liou, A.P., et al. (2013). Conserved shifts in the gut microbiota due to gastric bypass reduce host weight and adiposity. Science translational medicine, 5(178), 178ra41-178ra41.
Producción de metabolitos
1. Dorrestein, P.C., et al. (2014). Finding the missing links among metabolites, microbes, and the host. Immunity, 40(6), 824-832.
2. Gerhauser, C. (2018). Impact of dietary gut microbial metabolites on the epigenome. Philosophical Transactions of the Royal Society B: Biological Sciences, 373(1748), 20170359
Producción de vitaminas
1. LeBlanc, J. G., et al. (2011). B‐Group vitamin production by lactic acid bacteria–current knowledge and potential applications. Journal of applied microbiology, 111(6), 1297-1309.
2. LeBlanc, J. G., et al. (2013). Bacteria as vitamin suppliers to their host: a gut microbiota perspective. Current opinion in biotechnology, 24(2), 160-168.
Producción de neurotransmisores
1. Yano, J. M., et al. (2015). Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis. Cell, 161(2), 264-276.
Environmental influences
Los antibióticos y el microbioma
1. Langdon, A., et al. (2016). The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation. Genome medicine, 8(1), 39.
2. Dethlefsen, L., & Relman, D. A. (2011). Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proceedings of the National Academy of Sciences, 108(Supplement 1), 4554-4561.
3. Lange, K., et al. (2016). Effects of antibiotics on gut microbiota. Digestive Diseases, 34(3), 260-268.
4. Blaser, M. J. (2016). Antibiotic use and its consequences for the normal microbiome. Science, 352(6285), 544-545.
5. Jernberg, C., et al. (2007). Long-term ecological impacts of antibiotic administration on the human intestinal microbiota. The ISME journal, 1(1), 56.
La falta de sueño y el microbioma
1. Benedict, C., et al. (2016). Gut microbiota and glucometabolic alterations in response to recurrent partial sleep deprivation in normal-weight young individuals. Molecular metabolism, 5(12), 1175-1186.
2. Reynolds, A. C. et al. (2017). The shift work and health research agenda: considering changes in gut microbiota as a pathway linking shift work, sleep loss and circadian misalignment, and metabolic disease. Sleep medicine reviews, 34, 3-9.
El tabaco y el microbioma
1. Savin, Z., et al. (2018). Smoking and the intestinal microbiome. Archives of microbiology, 200(5), 677-684.
La alimentación y el microbioma
1. Singh, R. K., et al. (2017). Influence of diet on the gut microbiome and implications for human health. Journal of translational medicine, 15(1), 73.
2. David, L. A., et al. (2014). Diet rapidly and reproducibly alters the human gut microbiome. Nature, 505(7484), 559.
3. Biesalski, H. K. (2016). Nutrition meets the microbiome: micronutrients and the microbiota. Annals of the New York Academy of Sciences, 1372(1), 53-64.
4. Albenberg, L. G., & Wu, G. D. (2014). Diet and the intestinal microbiome: associations, functions, and implications for health and disease. Gastroenterology, 146(6), 1564-1572.
5. De Filippo, C., et al. (2010). Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proceedings of the National Academy of Sciences, 107(33), 14691-14696.
6. Huang, E. Y., et al. (2013). The role of diet in triggering human inflammatory disorders in the modern age. Microbes and Infection, 15(12), 765-774.
7. Sonnenburg, E. D., & Sonnenburg, J. L. (2014). Starving our microbial self: the deleterious consequences of a diet deficient in microbiota-accessible carbohydrates. Cell metabolism, 20(5), 779-786.
Los edulcorantes, los emulgentes y el microbioma
1. Suez, J., et al. (2014). Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature, 514(7521), 181.
2. Chassaing, B., et al. (2015). Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. Nature, 519(7541), 92.
3. Cani, P. D. (2015). Metabolism: Dietary emulsifiers—sweepers of the gut lining?. Nature Reviews Endocrinology, 11(6), 319.
La fibra y el microbioma
1. Slavin, J. (2013). Fiber and prebiotics: mechanisms and health benefits. Nutrients, 5(4), 1417-1435.
2. So, D., et al. (2018). Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis. The American journal of clinical nutrition, 107(6), 965-983.
Los probióticos
¿Qué son y cómo actúan los probióticos?
1. Markowiak, P., & Śliżewska, K. (2017). Effects of probiotics, prebiotics, and synbiotics on human health. Nutrients, 9(9), 1021.
2. Reid, G. (2016). Probiotics: definition, scope and mechanisms of action. Best Practice & Research Clinical Gastroenterology, 30(1), 17-25.
3. Bermudez-Brito, M., et al. (2012). Probiotic mechanisms of action. Annals of Nutrition and Metabolism, 61(2), 160-174.
4. Corr, S. C., et al. (2009). Understanding the mechanisms by which probiotics inhibit gastrointestinal pathogens. Advances in food and nutrition research, 56, 1-15.
5. Hemarajata, P., & Versalovic, J. (2013). Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation. Therapeutic advances in gastroenterology, 6(1), 39-51.
6. Lebeer, S., et al. (2018). Identification of probiotic effector molecules: present state and future perspectives. Current opinion in biotechnology, 49, 217-223.
7. Krishna Rao, R., & Samak, G. (2013). Protection and restitution of gut barrier by probiotics: nutritional and clinical implications. Current Nutrition & Food Science, 9(2), 99-107.
8. Bezkorovainy, A. (2001). Probiotics: determinants of survival and growth in the gut. The American journal of clinical nutrition, 73(2), 399s-405s.
Los prebióticos y los extractos vegetales
Prebióticos: general
1. Gibson, G. R., et al. (2017). Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nature reviews Gastroenterology & hepatology, 14(8), 491.
2. Gibson, G. R., & Roberfroid, M. B. (1995). Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. The Journal of nutrition, 125(6), 1401-1412.
3. Van Loo, J., et al. (1999). Functional food properties of non-digestible oligosaccharides: a consensus report from the ENDO project (DGXII AIRII-CT94-1095). British Journal of Nutrition, 81(2), 121-132.
4. Collins, S., & Reid, G. (2016). Distant site effects of ingested prebiotics. Nutrients, 8(9), 523.
5. Macfarlane, G. T., et al. (2008). Bacterial metabolism and health‐related effects of galacto‐oligosaccharides and other prebiotics. Journal of applied microbiology, 104(2), 305-344.
6. Al-Sheraji, S. Het al. (2013). Prebiotics as functional foods: A review. Journal of functional foods, 5(4), 1542-1553.
Inulin
1. Gibson, G. et al. (1995). Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterology, 108(4), 975-982.
2. Carlson, J.L., et al. (2018). Health effects and sources of prebiotic dietary fiber. Current developments in nutrition, 2(3), nzy005.
3. Guess, N.D., et al. (2015). A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutrition & metabolism, 12(1), 36.
Los polifenoles y el microbioma
1. Etxeberria, U., et al. (2013). Impact of polyphenols and polyphenol-rich dietary sources on gut microbiota composition. Journal of agricultural and food chemistry, 61(40), 9517-9533.
2. Cardona, F., Andrés-Lacueva, C., et al. (2013). Benefits of polyphenols on gut microbiota and implications in human health. The Journal of nutritional biochemistry, 24(8), 1415-1422.
3. Les, F., et al. (2018). Pomegranate polyphenols and urolithin A inhibit α-glucosidase, dipeptidyl peptidase-4, lipase, triglyceride accumulation and adipogenesis related genes in 3T3-L1 adipocyte-like cells. Journal of ethnopharmacology, 220, 67-74.
4. Thilakarathna, W.W., et al. (2018). Polyphenol-based prebiotics and synbiotics: potential for cancer chemoprevention. Current Opinion in Food Science, 20, 51-57.
Raíz de achicoria
1. Nishimura, M., et al. (2015). Effects of the extract from roasted chicory (Cichorium intybus L.) root containing inulin-type fructans on blood glucose, lipid metabolism, and fecal properties. Journal of traditional and complementary medicine, 5(3), 161-167.
2. Atta, A.H., et al. (2010). Hepatoprotective effect of methanol extracts of Zingiber officinale and Cichorium intybus. Indian journal of pharmaceutical sciences, 72(5), 564.
3. Kleessen, B., et al. (2007). Jerusalem artichoke and chicory inulin in bakery products affect faecal microbiota of healthy volunteers. British Journal of Nutrition, 98(3), 540-549.
Granada
1. Les, F., et al. (2018). Pomegranate polyphenols and urolithin A inhibit α-glucosidase, dipeptidyl peptidase-4, lipase, triglyceride accumulation and adipogenesis related genes in 3T3-L1 adipocyte-like cells. Journal of ethnopharmacology, 220, 67-74.
2. Andreux, P.A., et al. (2019). The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nature Metabolism, 1(6), 595.
Las Dailybacs
Tubo digestivo
1. Saggioro, A. (2004). Probiotics in the treatment of irritable bowel syndrome. Journal of clinical gastroenterology, 38, S104-S106.
2. Martínez-Martínez, M. I, et al. (2017). The effect of probiotics as a treatment for constipation in elderly people: A systematic review. Archives of gerontology and geriatrics, 71, 142-149.
3. Del Piano, M., et al. (2010). The use of probiotics in healthy volunteers with evacuation disorders and hard stools: a double-blind, randomized, placebo-controlled study. Journal of clinical gastroenterology, 44, S30-S34.
4. Klemenak, M., et al. (2015). Administration of Bifidobacterium breve Decreases the Production of TNF-α in Children with Celiac Disease. Digestive diseases and sciences, 60(11), 3386-3392.
5. Del Piano, M., et al. (2008). In vitro sensitivity of probiotics to human pancreatic juice. Journal of clinical gastroenterology, 42, S170-S173.
6. Mogna, L., et al. (2012). Assessment of the in vitro inhibitory activity of specific probiotic bacteria against different Escherichia coli strains. Journal of clinical gastroenterology, 46, S29-S32.
7. Del Piano, M., et al. (2014). Correlation between chronic treatment with proton pump inhibitors and bacterial overgrowth in the stomach: any possible beneficial role for selected lactobacilli?. Journal of clinical gastroenterology, 48, S40-S46.
8. Dimidi, E., et al. (2014). The effect of probiotics on functional constipation in adults: a systematic review and meta-analysis of randomized controlled trials. The American journal of clinical nutrition, 100(4), 1075-1084.
9. Ogata, T., et al. (1997). Effect of Bifidobacterium longum BB536 administration on the intestinal environment, defecation frequency and fecal characteristics of human volunteers. Bioscience and Microflora, 16(2), 53-58.d controlled trials. The American journal of clinical nutrition, 100(4), 1075-1084.
10. Odamaki, T., et al. (2012). Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota. Anaerobic, 18(1), 14-18.
11. Del Piano, M., et al. (2012). The innovative potential of Lactobacillus rhamnosus LR06, Lactobacillus pentosus LPS01, Lactobacillus plantarum LP01, and Lactobacillus delbrueckii Subsp. delbrueckii LDD01 to restore the “gastric barrier effect” in patients chronically treated with PPI: a pilot study.Journal of clinical gastroenterology, 46, S18-S26.
12. Islam, S. U (2016). Clinical uses of probiotics. Medicine, 95(5).
13. Kajander, K., et al. (2005). A probiotic mixture alleviates symptoms in irritable bowel syndrome patients: a controlled 6‐month intervention. Alimentary pharmacology & therapeutics, 22(5), 387-394.
14. Francavilla, R., et al. (2010). A randomized controlled trial of Lactobacillus GG in children with functional abdominal pain. Pediatrics, 126(6), e1445-e1452.
15. Gawronska, A., et al. (2007). A randomized double-blind placebo-controlled trial of Lactobacillus GG for abdominal pain disorders in children. Alimentary pharmacology & therapeutics, 25(2), 177-184.
16. Odamaki, T., et al. (2012). Effect of the oral intake of yogurt containing Bifidobacterium longum BB536 on the cell numbers of enterotoxigenic Bacteroides fragilis in microbiota. Anaerobic, 18(1), 14-18.
Sistema cardiovascular
1. Noad, R.L., et al. (2016). Beneficial effect of a polyphenol-rich diet on cardiovascular risk: a randomized control trial. Heart, 102(17), 1371-1379.
2. Nishimura, M., et al. (2015). Effects of the extract from roasted chicory (Cichorium intybus L.) root containing inulin-type fructans on blood glucose, lipid metabolism, and fecal properties. Journal of traditional and complementary medicine, 5(3), 161-167.
3. Guess, N.D., et al. (2015). A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutrition & metabolism, 12(1), 36.
4. Andrade, S., & Borges, N. (2009). Effect of fermented milk containing Lactobacillus acidophilus and Bifidobacterium longum on plasma lipids of women with normal or moderately elevated cholesterol. Journal of dairy research, 76(4), 469-474.
Mente
1. Huang, R., et al. (2017). Efficacy of probiotics on anxiety: A meta-analysis of randomized controlled trials. Neuropsychiatry, 7(6), 862-871.
2. Kim, C.S., & Shin, D.M. (2019). Probiotic food consumption is associated with lower severity and prevalence of depression: A nationwide cross-sectional study. Nutrition, 63, 169-174.
3. Smith, A., et al. (2015). An investigation of the acute effects of oligofructose-enriched inulin on subjective wellbeing, mood and cognitive performance. Nutrients, 7(11), 8887-8896.
4. Srikantha, P., & Mohajeri, M. H. (2019). The Possible Role of the Microbiota-Gut-Brain Axis in Autism Spectrum Disorder. International journal of molecular sciences, 20(9), 2115.
5. Pärtty, A., et al. (2015). A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial. Pediatric research, 77(6), 823.
Células
1. Amaretti, A., et al. (2013). Antioxidant properties of potentially probiotic bacteria: in vitro and in vivo activities. Applied microbiology and biotechnology, 97(2), 809-817.
2. Kerimi, A., & Williamson, G. (2016). At the interface of antioxidant signaling and cellular function: Key polyphenol effects. Molecular nutrition & food research, 60(8), 1770-1788.
Alergias
1. Drago, L., et al. (2015). Immunomodulatory effects of Lactobacillus salivarius LS01 and Bifidobacterium breve BR03, alone and in combination, on peripheral blood mononuclear cells of allergic asthmatics. Allergy, asthma & immunology research, 7(4), 409-413.
2. Manzotti, G., et al. (2014). Multi-strain Symbiotic Preparations as a Novel Adjuvant Approach to Allergic Rhinitis. Journal of Contemporary Immunology. 1. 67-80.
3. Enomoto, T., et al. (2014). Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergology International, 63(4), 575-585.
4. Xiao, J.Z., et al. (2006). Probiotics in the treatment of Japanese cedar pollinosis: a double-blind placebo-controlled trial. Clinical & Experimental Allergy, 36(11), 1425-1435.
5.Xiao, J.Z., et al. (2007). Clinical efficacy of probiotic Bifidobacterium longum for the treatment of symptoms of Japanese cedar pollen allergy in subjects evaluated in an environmental exposure unit. Allergology international, 56(1), 67-75.
Procesos metabólicos
1.Les, F., et al. (2018). Pomegranate polyphenols and urolithin A inhibit α-glucosidase, dipeptidyl peptidase-4, lipase, triglyceride accumulation and adipogenesis related genes in 3T3-L1 adipocyte-like cells. Journal of ethnopharmacology, 220, 67-74.
2. Ryu, D., et al. (2016). Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nature medicine, 22(8), 879.
3. Thilakarathna, W.W., et al. (2018). Polyphenol-based prebiotics and synbiotics: potential for cancer chemoprevention. Current Opinion in Food Science, 20, 51-57.
4. Andreux, P.A., et al. (2019). The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nature Metabolism, 1(6), 595.
5.Guess, N.D., et al. (2015). A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes. Nutrition & metabolism, 12(1), 36.
6. Minami, J.I., et al. (2015). Oral administration of Bifidobacterium breve B-3 modifies metabolic functions in adults with obese tendencies in a randomized controlled trial. Journal of nutritional science, 4.
7. Minami, J., et al. (2018). Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: a randomized, double-blind, placebo-controlled trial. Bioscience of microbiota, food and health, 18-001.
8.Mogna, L., et al. (2014). Screening of different probiotic strains for their in vitro ability to metabolize oxalates: any prospective use in humans?. Journal of clinical gastroenterology, 48, S91-S95.
Sistema inmune
1. Pregliasco, F., et al. (2008). A new chance of preventing winter diseases by the administration of synbiotic formulations. Journal of clinical gastroenterology, 42, S224-S233.
2. Klemenak, M., et al. (2015). Administration of Bifidobacterium breve Decreases the Production of TNF-α in Children with Celiac Disease. Digestive diseases and sciences, 60(11), 3386-3392.
3. Sugahara, H., et al. (2015). Probiotic Bifidobacterium longum alters gut luminal metabolism through modification of the gut microbial community. Scientific reports, 5, 13548.
4. Nicola, S., et al. (2010). Interaction between probiotics and human immune cells. Focus Diet Fibers Pre/Probiot, 21, 9-12.
5. Mogna, L., et al. (2018). Micronized Cells of the Probiotic Strain Bifidobacterium lactis BS01 Activate Monocyte Polarization: A New Approach. Journal of clinical gastroenterology, 52, S57-S61.
Piel
Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota.3
1. Manzotti, G., et al. (2014). Probiotics as a Novel Adjuvant Approach to Atopic Dermatitis. Journal of Contemporary Immunology, 1. 57-66.
2. Lemoli, E., et al. (2012). Probiotics reduce gut microbial translocation and improve adult atopic dermatitis. Journal of clinical gastroenterology, 46, S33-S40.
3. Enomoto, T., et al. (2014). Effects of bifidobacterial supplementation to pregnant women and infants in the prevention of allergy development in infants and on fecal microbiota. Allergology International, 63(4), 575-585.
Boca y dientes
1. Del Piano, M., et al. (2014). Correlation between Specific Bacterial Groups in the Oral Cavity and the Severity of Halitosis: Any Possible Beneficial Role for Selected Lactobacilli. J Gastroint Dig Syst, 4(197), 2.
2.Näse, L., et al. (2001). Effect of long–term consumption of a probiotic bacterium, Lactobacillus rhamnosus GG, in milk on dental caries and caries risk in children. Caries research, 35(6), 412-420.
Vejiga
1. Vicariotto, F. (2014). Effectiveness of an association of a cranberry dry extract, D-mannose, and the two microorganisms Lactobacillus plantarum LP01 and Lactobacillus paracasei LPC09 in women affected by cystitis: a pilot study. Journal of clinical gastroenterology, 48, S96-S101.
Mujeres
1. Holloway, L., et al. (2007). Effects of oligofructose-enriched inulin on intestinal absorption of calcium and magnesium and bone turnover markers in postmenopausal women. British Journal of Nutrition, 97(2), 365-372.
2. de Brito Alves, J. L., et al. (2019). Gut microbiota and probiotic intervention as a promising therapeutic for pregnant women with cardiometabolic disorders: present and future directions. Pharmacological research, 104252.
3. Han, M. M., et al. (2019). Probiotics improve glucose and lipid metabolism in pregnant women: a meta-analysis. Annals of translational medicine, 7(5).
4. Reid, G. (2016). The development of probiotics for women’s health. Canadian journal of microbiology, 63(4), 269-277.
5. Ocaña, V. S., et al. (1999). Characterization of a bacteriocin-like substance produced by a vaginal Lactobacillus salivariusstrain. Environ. Microbiol., 65(12), 5631-5635.
6. Ocaña, V., & Nader-Macías, M. E. (2001). Adhesion of Lactobacillus vaginal strains with probiotic properties to vaginal epithelial cells. Biocell: official journal of the Sociedades Latinoamericanas de Microscopia Electronica... et. al, 25(3), 265-273.
7. Ocaña, V. S., & Nader-Macías, M. E. (2002). Vaginal lactobacilli: self-and co-aggregating ability. British journal of biomedical science, 59(4), 183-190.
8. Zárate, G., & Nader‐Macias, M. E. (2006). Influence of probiotic vaginal lactobacilli on in vitro adhesion of urogenital pathogens to vaginal epithelial cells. Letters in Applied Microbiology, 43(2), 174-180.
9. Ocaña, V. S., et al. (1999). Surface characteristics of lactobacilli isolated from human vagina. The Journal of general and applied microbiology, 45(5), 203-212.
10. Tomás, J., et al. (2002). Influence of pH, temperature and culture media on the growth and bacteriocin production by vaginal Lactobacillus salivarius CRL 1328. Journal of Applied Microbiology, 93(4), 714-724.
11. Tomás, J., et al. (2005). Characterisation of potentially probiotic vaginal lactobacilli isolated from Argentinean women. British journal of biomedical science, 62(4), 170-174.
Hombres
1.Chen, X. L., et al. (2013). Antioxidative activity and protective effect of probiotics against high-fat diet-induced sperm damage in rats. Animal, 7(2), 287-292.
2. Nichols, A. W. (2007). Probiotics and athletic performance: a systematic review. Current sports medicine reports, 6(4), 269-273.
Niños
1. Clark, A. K., et al. (2017). Edible plants and their influence on the gut microbiome and acne. International journal of molecular sciences, 18(5), 1070.
2. Li, K. L., et al. (2019). Alterations of intestinal flora and the effects of probiotics in children with recurrent respiratory tract infection. World Journal of Pediatrics, 1-7.
3. Srikantha, P., & Mohajeri, M. H. (2019). The Possible Role of the Microbiota-Gut-Brain-Axis in Autism Spectrum Disorder. International journal of molecular sciences, 20(9), 2115.
4. Abrams, S. A., et al. (2005). A combination of prebiotic short-and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents–. The American journal of clinical nutrition, 82(2), 471-476.
5. Ishizeki, S., et al. (2013). Effect of administration of bifidobacteria on intestinal microbiota in low-birth-weight infants and transition of administered bifidobacteria: a comparison between one-species and three-species administration. Anaerobe, 23, 38-44.
Dermabacs
Akne
Facial Acne: A Randomized, Double-Blind, Placebo-Controlled Study on the Clinical Efficacy of a Symbiotic Dietary Supplement.3
Prospective, randomized, open-label trial comparing the safety, efficacy, and tolerability of an acne treatment regimen with and without a probiotic supplement and minocycline in subjects with mild to moderate acne.4
Dietary effect of lactoferrin-enriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris.5
Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis.6
The role of zinc in the treatment of acne: A review of the literature. 7
1. Deidda, F., Amoruso, A., Nicola, S., Graziano, T., Pane, M., & Mogna, L. (2018). New Approach in Acne Therapy: A Specific Bacteriocin Activity and a Targeted Anti IL-8 Property in Just 1 Probiotic Strain, the: L. salivarius: LS03. Journal of clinical gastroenterology, 52, S78-S81.
2. Bowe, W. P., Filip, J. C., DiRienzo, J. M., Volgina, A., & Margolis, D. J. (2006). Inhibition of propionibacterium acnes by bacteriocin-like inhibitory substances (BLIS) produced by Streptococcus salivarius. Journal of drugs in dermatology : JDD, 5(9), 868–870.
3. Rinaldi, F., Marotta, L., Mascolo, A., Amoruso, A., Pane, M., Giuliani, G., & Pinto, D. (2022). Facial Acne: A Randomized, Double-Blind, Placebo-Controlled Study on the Clinical Efficacy of a Symbiotic Dietary Supplement. Dermatology and therapy, 12(2), 577–589. https://doi.org/10.1007/s13555-021-00664-z
4. Jung, G. W., Tse, J. E., Guiha, I., & Rao, J. (2013). Prospective, randomized, open-label trial comparing the safety, efficacy, and tolerability of an acne treatment regimen with and without a probiotic supplement and minocycline in subjects with mild to moderate acne. Journal of cutaneous medicine and surgery, 17(2), 114–122. https://doi.org/10.2310/7750.2012.12026
5. Kim, J., Ko, Y., Park, Y. K., Kim, N. I., Ha, W. K., & Cho, Y. (2010). Dietary effect of lactoferrin-enriched fermented milk on skin surface lipid and clinical improvement of acne vulgaris. Nutrition (Burbank, Los Angeles County, Calif.), 26(9), 902–909. https://doi.org/10.1016/j.nut.2010.05.011
6. Yee, B. E., Richards, P., Sui, J. Y., & Marsch, A. F. (2020). Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta‐analysis. Dermatologic therapy, 33(6), e14252.
7. Cervantes J, Eber AE, Perper M, Nascimento VM, Nouri K, Keri JE. The role of zinc in the treatment of acne: A review of the literature. Dermatol Ther. 2018 Jan;31(1). doi: 10.1111/dth.12576. Epub 2017 Nov 28. PMID: 29193602.
Rosacea
1. Fortuna, M. C., Garelli, V., Pranteda, G., Romaniello, F., Cardone, M., Carlesimo, M., & Rossi, A. (2016). A case of Scalp Rosacea treated with low dose doxycycline and probiotic therapy and literature review on therapeutic options. Dermatologic therapy, 29(4), 249–251. https://doi.org/10.1111/dth.12355
2. Sharquie KE, Najim RA, Al-Salman HN. Oral zinc sulfate in the treatment of rosacea: a double-blind, placebo-controlled study. Int J Dermatol. 2006 Jul;45(7):857-61. doi: 10.1111/j.1365-4632.2006.02944.x. PMID: 16863527.
Atopic Dermatitis
Treatment of atopic dermatitis eczema with a high concentration of Lactobacillus salivarius LS01 associated with an innovative gelling complex: a pilot study on adults.3
Effect of Oral Administration of a Mixture of Probiotic Strains on SCORAD Index and Use of Topical Steroids in Young Patients With Moderate Atopic Dermatitis.4
Changes in Gut Microbiota Correlates with Response to Treatment with Probiotics in Patients with Atopic Dermatitis. A Post Hoc Analysis of a Clinical Trial.5
Lactobacillus rhamnosus GG Inhibits the Toxic Effects of Staphylococcus aureus on Epidermal Keratinocytes.6
1. Manzotti, G., Fassio, F., & Heffler, E. (2014). Probiotics as a Novel Adjuvant Approach to Atopic Dermatitis. JOURNAL OF CONTEMPORARY IMMUNOLOGY, 1(2), 57-66.
2. https://doi.org/10.1097/MCG.0000000000000249 Farid, R., Ahanchian, H., Jabbari, F., & Moghiman, T. (2011). Effect of a new synbiotic mixture on atopic dermatitis in children: a randomized-controlled trial. Iranian journal of pediatrics, 21(2), 225–230. https://doi.org/10.1111/dth.12355
3. Drago, L., De Vecchi, E., Toscano, M., Vassena, C., Altomare, G., & Pigatto, P. (2014). Treatment of atopic dermatitis eczema with a high concentration of Lactobacillus salivarius LS01 associated with an innovative gelling complex: a pilot study on adults. Journal of clinical gastroenterology, 48 Suppl 1, S47–S51. https://doi.org/10.1097/MCG.0000000000000249
4. Navarro-López V, Ramírez-Boscá A, Ramón-Vidal D, et al. Effect of Oral Administration of a Mixture of Probiotic Strains on SCORAD Index and Use of Topical Steroids in Young Patients With Moderate Atopic Dermatitis: A Randomized Clinical Trial. JAMA Dermatol. 2018;154(1):37-43. doi:10.1001/jamadermatol.2017.3647
5. Climent E, Martinez-Blanch JF, Llobregat L, Ruzafa-Costas B, Carrión-Gutiérrez MÁ, Ramírez-Boscá A, Prieto-Merino D, Genovés S, Codoñer FM, Ramón D, Chenoll E, Navarro-López V. Changes in Gut Microbiota Correlates with Response to Treatment with Probiotics in Patients with Atopic Dermatitis. A Post Hoc Analysis of a Clinical Trial. Microorganisms. 2021 Apr 15;9(4):854. doi: 10.3390/microorganisms9040854. PMID: 33921166; PMCID: PMC8071520.
6. Mohammedsaeed, W., McBain, A. J., Cruickshank, S. M., & O'Neill, C. A. (2014). Lactobacillus rhamnosus GG inhibits the toxic effects of Staphylococcus aureus on epidermal keratinocytes. Applied and environmental microbiology, 80(18), 5773–5781. https://doi.org/10.1128/AEM.00861-14
Daily Greens
Fibra alimentaria
1. Holscher, H. D. (2017). Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut Microbes, 8(2), 172–184. https://doi.org/10.1080/19490976.2017.1290756.
2. Beane, K.E., Redding, M.C., Wang, X. et al. Effects of dietary fibers, micronutrients, and phytonutrients on gut microbiome: a review. Appl Biol Chem 64, 36 (2021). https://doi.org/10.1186/s13765-021-00605-6.
3.Soliman G. A. (2019). Dietary Fiber, Atherosclerosis, and Cardiovascular Disease. Nutrients, 11(5), 1155. https://doi.org/10.3390/nu11051155
4.Reynolds, A. N., Akerman, A., Kumar, S., Diep Pham, H. T., Coffey, S., & Mann, J. (2022). Dietary fibre in hypertension and cardiovascular disease management: systematic review and meta-analyses. BMC medicine, 20(1), 139. https://doi.org/10.1186/s12916-022-02328-x.
5. Kaczmarczyk, M. M., Miller, M. J., & Freund, G. G. (2012). The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer. Metabolism: clinical and experimental, 61(8), 1058–1066. https://doi.org/10.1016/j.metabol.2012.01.017.
6. Lu, K., Yu, T., Cao, X., Xia, H., Wang, S., Sun, G., Chen, L., & Liao, W. (2023). Effect of viscous soluble dietary fiber on glucose and lipid metabolism in patients with type 2 diabetes mellitus: a systematic review and meta-analysis on randomized clinical trials. Frontiers in nutrition, 10, 1253312. https://doi.org/10.3389/fnut.2023.1253312.
Dietbacs
Gastrointestinal
1. Michael, D. R., Jack, A. A., Masetti, G., Davies, T. S., Loxley, K. E., Kerry-Smith, J., Plummer, J. F., Marchesi, J. R., Mullish, B. H., McDonald, J. A. K., Hughes, T. R., Wang, D., Garaiova, I., Paduchová, Z., Muchová, J., Good, M. A., & Plummer, S. F. (2020). A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well-being. Scientific reports, 10(1), 4183.
2. Michael, D. R., Davies, T. S., Jack, A. A., Masetti, G., Marchesi, J. R., Wang, D., ... & Plummer, S. F. (2021). Daily supplementation with the Lab4P probiotic consortium induces significant weight loss in overweight adults. Scientific reports, 11(1), 5./doi.org/10.1128/AEM.00861-14
Dailybacs Kids
Promover el equilibrio en los intestinos
1. Keikha, M., & Karbalaei, M. (2021). Probiotics as the live microscopic fighters against Helicobacter pylori gastric infections. BMC Gastroenterology, 21(1).
2.Solito, A., Hasballa, I., Calgaro, M., Bozzi, C. N., Ricotti, R., Caputo, M., Genoni, G., Monzani, A., Archero, F., Bellone, S., Bona, G., Agosti, E., Aimaretti, G., Amoruso, A., Pane, M., Vitulo, N., Di, G. D., & Prodam, F. (2020). Supplementation with Bifidobacterium breve BR03 and Bifidobacterium breve B632 favoured weight loss and improved insulin metabolism in children and adolescents with obesity in the BIFI-OBESE cross-over, randomized placebo-controlled trial. Endocrine Abstracts.
3. Drago, L., Meroni, G., Chiaretti, A., Laforgia, N., Cucchiara, S., & Baldassarre, M. (2020). Effect of Limosilactobacillus reuteri LRE02–lacticaseibacillus rhamnosus LR04 combination on antibiotic-associated diarrhea in a pediatric population: A national survey. Journal of Clinical Medicine, 9(10), 3080.
4. Chamignon, C., Guéneau, V., Medina, S., Deschamps, J., Gil-Izquierdo, A., Briandet, R., Mousset, P., Langella, P., Lafay, S., & Bermúdez-Humarán, L. G. (2020). Evaluation of the probiotic properties and the capacity to form Biofilms of various lactobacillus strains. Microorganisms, 8(7), 1053.
5. Kara, S., Volkan, B., & Erten, I. (2019). Lactobacillus rhamnosusGG can protect malnourished children. Beneficial Microbes, 10(3), 237-244.
6.Nixon, A. F., Cunningham, S. J., Cohen, H. W., & Crain, E. F. (2012). The effect of lactobacillus GG on acute diarrheal illness in the pediatric emergency department. Pediatric Emergency Care, 28(10), 1048-1051.
7.Lam, E. K., Tai, E. K., Koo, M. W., Wong, H. P., Wu, W. K., Yu, L., So, W. H., Woo, P. C., & Cho, C. (2007). Enhancement of gastric mucosal integrity by lactobacillus rhamnosus GG. Life Sciences, 80(23), 2128-2136.
8.Mack, D. R. (2003). Extracellular MUC3 mucin secretion follows adherence of lactobacillus strains to intestinal epithelial cells in vitro. Gut, 52(6), 827-833. https://doi.org/10.1136/gut.52.6.827.
Fortalecimiento del sistema inmunológico
1. Approach to probiotics in pediatrics: The role of lactobacillus rhamnosus GG. (2022). Archivos Argentinos de Pediatria, 120(1).
2.Keikha, M., & Karbalaei, M. (2021). Probiotics as the live microscopic fighters against Helicobacter pylori gastric infections. BMC Gastroenterology, 21(1).
3. Ferrari, E., Monzani, R., Saverio, V., Gagliardi, M., Pańczyszyn, E., Raia, V., Villella, V. R., Bona, G., Pane, M., Amoruso, A., & Corazzari, M. (2021). Probiotics supplements reduce ER stress and gut inflammation associated with gliadin intake in a mouse model of gluten sensitivity. Nutrients, 13(4), 1221.
4.Primec, M., Klemenak, M., Di Gioia, D., Aloisio, I., Bozzi Cionci, N., Quagliariello, A., Gorenjak, M., Mičetić-Turk, D., & Langerholc, T. (2019). Clinical intervention using Bifidobacterium strains in celiac disease children reveals novel microbial modulators of TNF-α and short-chain fatty acids. Clinical Nutrition, 38(3), 1373-1381.
5.Quagliariello, A., Aloisio, I., Bozzi Cionci, N., Luiselli, D., D’Auria, G., Martinez-Priego, L., Pérez-Villarroya, D., Langerholc, T., Primec, M., Mičetić-Turk, D., & Di Gioia, D. (2016). Effect of Bifidobacterium breve on the intestinal microbiota of coeliac children on a gluten free diet: A pilot study. Nutrients, 8(10), 660.
6. Klemenak, M., Dolinšek, J., Langerholc, T., Di Gioia, D., & Mičetić-Turk, D. (2015). Administration of Bifidobacterium breve decreases the production of TNF-α in children with celiac disease. Digestive Diseases and Sciences, 60(11), 3386-3392.
7. Berni Canani, R., Di Costanzo, M., Pezzella, V., Cosenza, L., Granata, V., Terrin, G., & Nocerino, R. (2012). The potential therapeutic efficacy of lactobacillus GG in children with food allergies. Pharmaceuticals, 5(6), 655-664.
Promover el desarrollo cognitivo
1. Sanborn, V., Azcarate-Peril, M. A., Updegraff, J., Manderino, L. M., & Gunstad, J. (2018). A randomized clinical trial examining the impact of LGG probiotic supplementation on psychological status in middle-aged and older adults. Contemporary Clinical Trials Communications, 12, 192-197.
Regulación del estado de ánimo
1. Kumperscak, H. G., Gricar, A., Ülen, I., & Micetic-Turk, D. (2020). A pilot randomized control trial with the probiotic strain lactobacillus rhamnosus GG (LGG) in ADHD: Children and adolescents report better health-related quality of life. Frontiers in Psychiatry, 11.