Subscribe for 3 months & secure free gifts worth €24.95 💚

TAKE THE TEST

products

Cart

Lactic Acid Bacteria in the Vagina: Their Role in the Vaginal Environment

Lactic acid bacteria in the vagina may initially sound like a specialized topic in microbiology to many. However, they are actually one of the central reasons why the vaginal environment remains stable in many women. Understanding the role these bacteria play in the intimate area also helps to better understand why topics like pH value, vaginal flora, and their natural balance are so closely connected.

 

 

Lactic Acid Bacteria and Lactobacilli in the Vagina: Which Types Are Meant?

In this context, lactic acid bacteria mainly refer to various Lactobacillus species. They naturally occur in different parts of the body — including the gut and, in many women, also in the vagina. They play an important role in the vaginal environment because they are closely linked to the natural balance and an acidic pH value. This environment is considered an important component of a stable vaginal milieu.


Lactic acid bacteria are therefore not just “present” but functionally relevant. Especially in the intimate area, they are closely related to the pH value and thus to the question of how stable or sensitive the vaginal flora is in each context.

 

Why Does the pH Value Play Such a Big Role?

The pH value is an important marker for the vaginal environment. A frequently cited in-vivo study shows that a Lactobacillus-dominated environment can be closely associated with a low, i.e., acidic pH level and a higher lactate concentration. In other words: These bacteria are not only part of the vaginal flora but measurably shape the chemical environment.


That is exactly why lactic acid bacteria appear in almost every discussion about vaginal flora, intimate imbalance, and pH value. They are not a lifestyle buzzword but biologically plausible and well described in their importance for the vaginal environment.

 

Does This Automatically Mean That Every Product with Lactobacillus Improves the Vaginal Flora?

Lactic acid bacteria are biologically highly relevant for the vaginal environment. At the same time, it is worth taking a differentiated look at how products in this area are evaluated. Which strains are included, whether they are taken orally or applied locally, in what context they are used, and which questions are being investigated can make a significant difference. Therefore, research increasingly speaks not only generally about “Lactobacillus” but more specifically about strains and applications.


Not all Lactobacillus strains show comparable effects, and results can only be transferred to a limited extent. Some strains are particularly frequently studied in connection with the vaginal flora — including Lactobacillus crispatus, Lactobacillus jensenii, Lactobacillus gasseri, and Lactobacillus iners, each of which can play different roles depending on the context.


Studies on Lactobacillus fermentum CS57 and Lactobacillus crispatus BC5 have shown that these strains can influence the mucous membrane in such a way that pathogens like Candida or Chlamydia have a harder time settling.
A randomized, double-blind, placebo-controlled study by Rapisarda et al. involving 60 women with vaginal dysbiosis showed that a specific orally administered Lactobacillus strain (Lacticaseibacillus rhamnosus CA15) can be associated with improvements in clinical symptoms as well as changes in microbial composition. These effects were still present 30 days after intake, while no comparable changes were observed in the placebo group.


Overall, the existing evidence shows that microbiological relationships in the intimate area cannot simply be reduced to general statements. This underscores the need for a differentiated view and argues for scientifically based communication that considers composition, context, and evidence instead of making simplified “rebuilding” promises.

 

What Does This Mean for Everyday Life?

For everyday life, this mainly means: A balanced vaginal environment is not a repair project if no symptoms are present. It is much more important to avoid factors that can unnecessarily disturb the balance — such as douching (vaginal rinsing), aggressive intimate products, or excessive cleaning. ACOG therefore recommends gentle care of the intimate area.
If symptoms occur, a clear assessment is also needed. Because burning, itching, odor, or discharge can have very different causes. That is why it is not very helpful to consider lactic acid bacteria as a cure-all. The context is crucial: Is there an imbalance, irritation, infection, or hormonally induced mucosal change?

 

Conclusion

Lactic acid bacteria are a key component of the vaginal environment — especially because they are closely linked to an acidic environment and the natural balance in the intimate area. However, this does not mean that every product with “Lactobacillus” automatically has a clear vaginal effect. This tension between biological plausibility, genuine research, and responsible communication deserves careful consideration.

sources

Pendharkar S, Brandsborg E, Hammarström L, Marcotte H, Larsson PG. Lactobacilli and Their Probiotic Effects in the Vagina of Reproductive Age Women. https://pubmed.ncbi.nlm.nih.gov/36985210/ O’Hanlon DE, Moench TR, Cone RA. Vaginal pH measured in vivo: lactobacilli determine pH and lactic acid concentration. https://pubmed.ncbi.nlm.nih.gov/30642259/ Lyra A, Hill C, O’Toole PW, et al. A Healthy Vaginal Microbiota Remains Stable during Oral Probiotic Supplementation. https://pubmed.ncbi.nlm.nih.gov/36838464/ ACOG. Vaginitis. https://www.acog.org/womens-health/faqs/vaginitis mybacs®. Drei Bakterienstämme und ihre besonderen Eigenschaften. https://mybacs.com/blogs/wissenschaft/die-drei-wichtigsten-bakterienstamme Chee WJY, Chew SY, Than LTL. Vaginal microbiota and the potential of Lactobacillus derivatives in maintaining vaginal health. Microbial Cell Factories. 2020,19:203. https://link.springer.com/article/10.1186/s12934-020-01464-4 Sabia C, Anacarso I, Bergonzini A, et al. Detection and partial characterization of a bacteriocin-like substance produced by Lactobacillus fermentum CS57 isolated from human vaginal secretions. Anaerobe. 2014,26:41-45. https://pubmed.ncbi.nlm.nih.gov/24462825/ Parolin C, Frisco G, Foschi C, et al. Lactobacillus crispatus BC5 Interferes With Chlamydia trachomatis Infectivity Through Integrin Modulation in Cervical Cells. Frontiers in Microbiology. 2018,9:2630. https://pubmed.ncbi.nlm.nih.gov/30459737/ Rapisarda AMC, Pino A, Grimaldi RL, Caggia C, Randazzo CL, Cianci A. Lacticaseibacillus rhamnosus CA15 (DSM 33960) strain as a new driver in restoring the normal vaginal microbiota: A randomized, double-blind, placebo-controlled clinical trial. Frontiers in Surgery. 2023 9:1075612. https://pubmed.ncbi.nlm.nih.gov/36700035/